Phenytoin induced severe disabling osteomalacia in a young male with seizure disorder.
Artigo
em Inglês
| IMSEAR
| ID: sea-94819
ABSTRACT
While the use of anti epileptic drugs (AEDs) for a long period is a known risk factor for bone loss and pathological fractures, yet the physicians are not yet sensitized to this possibility. It is now believed that the patients who have fractures due to long-term treatment with anticonvulsants have osteomalacia as the predominant lesion. This has been attributed to the alterations in the levels of circulating calcium and calcitropic hormones. Here we report a case of a young male who had been on anticonvulsants for 11 years and was admitted with us with severe bone pains, multiple pathological pseudo fractures and a severe degree of disability secondary to phenytoin induced osteomalacia.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Osteomalacia
/
Fenitoína
/
Humanos
/
Masculino
/
Adolescente
/
Epilepsia Tônico-Clônica
/
Assistência de Longa Duração
/
Avaliação da Deficiência
/
Encefalite
/
Índia
Tipo de estudo:
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
2008
Tipo de documento:
Artigo
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