Helicobacter pylori link to pernicious anaemia.
Artigo
em Inglês
| IMSEAR
| ID: sea-94904
ABSTRACT
An immunological classification of chronic gastritis based on the detection of Helicobacter pylori (H. pylori) antibody, parietal cell antibody, intrinsic factor antibody, is reported. H. pylori chronic gastritis, slowly progresses to atrophic gastritis, in the majority of patients; in a few patients, with genetic susceptibility to form intrinsic factor antibody, it progresses to pernicious anaemia. In majority of patients of pernicious anaemia, H. pylori gradually disappears from the gastric mucosa, on development of intestinal metaplasia in them. Atrophic gastritis results from H. pylori or non H. pylori. H. pylori infection is diagnosed in the presence of H. pylori in the gastric mucosal biopsy and/or H. pylori antibody (IgG) in the serum. The presence of the genetic factor (intrinsic factor antibody) is essential for the diagnosis of pernicious aneamia. Pernicious anaemia patients without intrinsic factor antibody, should be correctly diagnosed as atrophic gastritis, in view of the absence of the genetic factor (intrinsic factor antibody) in them.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Fatores de Risco
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Progressão da Doença
/
Gastrite Atrófica
/
Anemia Perniciosa
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Idioma:
Inglês
Ano de publicação:
2007
Tipo de documento:
Artigo
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