Prognosis and management of membraneous nephropathy.
Artigo
em Inglês
| IMSEAR
| ID: sea-95307
ABSTRACT
Patients of idiopathic membranous nephropathy (MGN) were randomly assigned to received steroid and cyclophosphamide every other month (Gr-I) and steroid alone (Gr-II). Of 36 patients in Gr.I, 33 patients achieved complete remissions, 2 had relapsing course with remission on further courses of therapy and only one has reached end stage renal failure. In contrast, of the 35 patients in Gr. II, 15 (P < 0.001) achieved complete remission, 7 are in partial remission, 5 have no response, another 5 have deterioration of renal function of which two required dialysis, and 3 have relapsing course after the initial remission. Mean follow up period was 46 +/- 10.2 months. We conclude that steroid and cyclophosphamide every other month is highly effective in achieving remission in patients with membranous nephropathy.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Prognóstico
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Esquema de Medicação
/
Prednisolona
/
Glomerulonefrite Membranosa
/
Seguimentos
/
Adolescente
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
1993
Tipo de documento:
Artigo
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