Familial childhood systemic lupus erythematosus: report of 2 cases.
J Indian Med Assoc
;
2007 Mar; 105(3): 141, 148
Artigo
em Inglês
| IMSEAR
| ID: sea-96613
ABSTRACT
Systemic lupus erythematosus is a multisystem organ inflammation due to damage of cells and tissues by pathogenic auto-antibodies and immune complexes. The most important factor for the causation of familial systemic lupus erythematosus is genetic on which environmental factor usually coexists. Two brothers of 7 and 3 years of age having childhood systemic lupus erythematosus are reported here because of low incidence and familial occurrence. Both the children fulfilled the American Rheumatology Association (ARA) criterion of systemic lupus erythematosus though anti-dsDNA was negative in both and antinuclear factor was positive only in the younger child. Systemic lupus erythematosus begins in childhood in 20% of adult patients and usually after the age of 8 years but here onset was even at an earlier age. The treatment of the both the siblings included administration of steroids and cyclophosphamide.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Masculino
/
Esquema de Medicação
/
Prednisolona
/
Criança
/
Pré-Escolar
/
Ciclofosfamida
/
Irmãos
/
Imunossupressores
/
Lúpus Eritematoso Sistêmico
Idioma:
Inglês
Revista:
J Indian Med Assoc
Ano de publicação:
2007
Tipo de documento:
Artigo
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