Intestinal amoebiasis: delayed-type hypersensitivity response in mice.
J Health Popul Nutr
;
2000 Sep; 18(2): 109-14
Artigo
em Inglês
| IMSEAR
| ID: sea-974
ABSTRACT
Delayed-type hypersensitive (DTH) response was evaluated in C3H/HeJ mice intestinally infected with Entamoeba histolytica. Infected and non-infected control mice were challenged with amoebic antigen on day 5, 10, 15, 20, 25, 30, 40, 50, and 60 post-infection. Maximum footpad swelling was observed after 24 hours of the challenge. The E. histolytica-infected mice exhibited a DTH response on day 5, 15, 20, 25, 40 and 60 post-infection. However, on day 10, 30, and 50, such response was similar to that of the non-infected control mice. The mice developed an evident DTH response late in the course of infection (25 days post-infection). The infected mice did not show any alteration to their DTH response against heterologous unrelated antigen (sheep red blood cells), suggesting that cellular anergy was antigen-specific.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fatores de Tempo
/
Modelos Animais de Doenças
/
Disenteria Amebiana
/
Entamoeba histolytica
/
Hipersensibilidade Tardia
/
Imunidade Celular
/
Animais
/
Camundongos
/
Camundongos Endogâmicos C3H
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
J Health Popul Nutr
Assunto da revista:
Gastroenterology
/
Nutritional Sciences
/
Public Health
Ano de publicação:
2000
Tipo de documento:
Artigo
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