Primary Antiphospholipid Antibody Syndrome: Neuro radiologic Findings in 11 Patients
Korean Journal of Radiology
; : 5-10, 2000.
Article
em En
| WPRIM
| ID: wpr-100201
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE: To describe the neuroradiologic findings of primary antiphospholipid antibody syndrome (PAPS). MATERIALS AND METHODS: During a recent two-year period, abnormally elevated antiphospholipid antibodies were detected in a total of 751 patients. In any cases in which risk factors for stroke were detected-hypertension, diabetes mellitus, hyperlipidemia, smoking, and the presence of SLE or other connective tissue diseases-PAPS was not diagnosed. Neuroradiologic studies were performed in 11 of 32 patients with PAPS. We retrospectively reviewed brain CT (n = 7), MR (n = 8), and cerebral angiography (n = 8) in 11 patients with special attention to the presence of brain parenchymal lesions and cerebral arterial or venous abnormalities. RESULTS: CT or MR findings of PAPS included nonspecific multiple hyper-inten-sity foci in deep white matter on T2-weighted images (5/11), a large infarct in the territory of the middle cerebral artery (4/11), diffuse cortical atrophy (2/11), focal hemorrhage (2/11), and dural sinus thrombosis (1/11). Angiographic findings were normal (5/8) or reflected either occlusion of a large cerebral artery (2/8) or dural sinus thrombosis (1/8). CONCLUSION: Neuroradiologic findings of PAPS are nonspecific but in young or middle-aged adults who show the above mentioned CT or MR findings, and in whom risk factors for stroke are not present, the condition should be suspected.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Encéfalo
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Imageamento por Ressonância Magnética
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Angiografia Cerebral
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Tomografia Computadorizada por Raios X
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Fatores de Risco
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Síndrome Antifosfolipídica
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Pessoa de Meia-Idade
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Korean Journal of Radiology
Ano de publicação:
2000
Tipo de documento:
Article