Does Neonatal Microbiome Research Encompass the Placental Transfer Pathway?
Neonatal Medicine
;
: 96-101, 2023.
Artigo
em Inglês
| WPRIM
| ID: wpr-1002552
ABSTRACT
The word “microbiome” is a combination of “microbiota” and “genome,” which represents the genomic concept of microbiota. The bacterial culture method is the mainstay of identifying microbes, while polymerase chain reaction adds diagnostic value. However, in the era of next-generation sequencing, achieving high-throughput microbiota footprints is extremely sensitive. This sensitivity often leads to confusion, as it can detect specific microbes genomes, even in sterile samples, such as blood, placenta, breast milk, skin, vagina, and stool. The neonatal microbiome remarkably influences both fetal and neonatal life related to health status and disease outcome. However, its origins pose a question does it stem from a direct gateway or through a breakdown of barriers? This review provides a brief overview of evidence and speculative insights.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Neonatal Medicine
Ano de publicação:
2023
Tipo de documento:
Artigo
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