Pterygoid botolinum toxin injection

ABSTRACT

@#Botolinum is a toxic polypeptide produced by the gram-positive anaerobic bacterium Clostridium botulinum that inhibits acetylcholine release from nerve endings, resulting in reduced neuromuscular transmission and local muscle activity, as well as cholinergic mediated parasympathetic activities.1 Its name is derived from the Latin word botulus, meaning sausage, as its toxicity was initially attributed to the oil of spoiled sausages. Of late, botolinum, packaged in various commercial forms such as onabotulinumtoxinA (Botox® type A, Allergan, Irvine, CA), is popularly used in several medical applications such as blepharospasm, hyperhidrosis and strabismus, and most famously in cosmetic surgery, where Botox® injections are used to eliminate and/or smoothen wrinkles.