Progress of researches on molecular mechanisms underlying helminth infection-mediated type 1/2 host immune responses / 中国血吸虫病防治杂志
Chinese Journal of Schistosomiasis Control
; (6): 534-538, 2023.
Article
em Zh
| WPRIM
| ID: wpr-1003614
Biblioteca responsável:
WPRO
ABSTRACT
Helminth infections are widespread worldwide, and pose a serious threat to human health and animal husbandry development. Understanding of helminth-host interactions is critical to effective control and ultimate eradication of helminthiasis. Following host infections, helminth infections firstly initiate innate immune responses and then mediate adaptive immune responses. Type 1 immune responses are predominant at early stage of helminth infections, which mainly play anti-infective actions, and type 2 immune responses are predominant at late stage of infections, which are associated with helminth immune evasion and aggravation of tissue damages. This review summarizes the progress of researches on type 1/2 immune responses-associated signaling pathways mediated by helminth infections in hosts.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Transdução de Sinais
/
Helmintíase
/
Helmintos
/
Interações Hospedeiro-Parasita
/
Imunidade Inata
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Chinese Journal of Schistosomiasis Control
Ano de publicação:
2023
Tipo de documento:
Article