Analysis of glycosylated hemoglobin in apheresis platelet donors / 中国输血杂志

ABSTRACT

【Objective】 To investigate the level of glycosylated hemoglobin (HbA1c) in apheresis platelet donors, so as to further ensure the safety of apheresis platelet donors and provide guidance for the recruitment strategy. 【Methods】 Apheresis platelet donors from July 2018 to December 2020 were selected and venous blood was drawn. The glycosylated hemoglobin detection was conducted for donors who had never did this before or did this 3 months ago, and glycosylated hemoglobin >6.0% was regarded as abnormal. 【Results】 A total of 986 blood donors were detected, among which 32 donors with abnormal glycosylated hemoglobin were found, rated at 3.25%. With the increase of age and BMI(height and body mass index), the proportion of abnormal glycosylated hemoglobin increased, but the 51~60 age group and BMI > 28.0 group were not the highest, which may be related to the source of samples.The rate of abnormal glycosylated hemoglobin was highest in 40~50 years old group (5.43%, 15 / 276) and BMI ranged of 24.0~27.9 (4.04%, 9 / 223), and lowest (0.85%, 1 / 118) in 18~25 years old group and BMI >28.0(none). 【Conclusion】 The abnormal glycosylated hemoglobin is closely related to age and BMI. Therefore, we should give priority to young and underweight donors when recruiting blood donors, which can improve efficiency and maximize the safety of blood donors.