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Analysis of HIV testing and reentry of voluntary blood donors / 中国输血杂志
Chinese Journal of Blood Transfusion ; (12): 292-295, 2022.
Artigo em Chinês | WPRIM | ID: wpr-1004368
ABSTRACT
【Objective】 To evaluate the rationality of detection method and the feasibility of the reentry strategy by analyzing HIV testing results and reentry data retrospectively. 【Methods】 From 2016 to 2020, dual ELISA and once NAT were performed in 501 074 voluntary blood donors for HIV detection. Reactive samples by either test were sent to Xuzhou CDC for Western blot (WB) confirmation test. A total of 102 donors who met the HIV reentry requirements and volunteered to return (interval ≥6 months) were tested by ELISA and NAT again. The negative samples were sent to Jiangsu Provincial Blood Center for confirmation and supplementary experiments, and the confirmed negative donors could return to the team. 【Results】 The reactive rate of one ELISA assay for anti-HIV in voluntary blood donors was 0.09%(447/501 074), and all confirmed anti-HIV negative by CDC. The reactive rate of double ELISA assays for anti-HIV was 0.02%(83/501 074), among which 53 were confirmed HIV infection by CDC, accounting for 0.01%(53/501 074). Among the 65 blood donors who met the reentry requirements and presented negative results, 61 returned to the team successfully by Jiangsu Provincial Blood Center. Forty-five of them donated blood again and 39 passed the screening test. However, the anti-HIV reactive rate (13.33%, 6/45) of reentry donors was still significantly higher than that of common donors (P<0.05). 【Conclusion】 Due to the high false positivity of one anti-HIV ELISA reagent, false reactive donors who deferred for gray area and and weak positivity of one ELISA assay should be informed the reentry procedure to reduce the waste of blood resources and eliminate the anxiety of blood donors on their own health, so as to promote the sustainable development of voluntary blood donation.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Blood Transfusion Ano de publicação: 2022 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Blood Transfusion Ano de publicação: 2022 Tipo de documento: Artigo