Association between serum gonadotropin level and insulin resistance-related parameters in Korean women with polycystic ovary syndrome
Obstetrics & Gynecology Science
;
: 498-505, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-100501
ABSTRACT
OBJECTIVE:
To evaluate the relationship between serum gonadotropin level and parameters related to insulin resistance in Korean women with polycystic ovary syndrome (PCOS).METHODS:
This retrospective study included 138 women aged 18 to 35 years who were newly diagnosed with PCOS according to the Rotterdam consensus. Participants were divided into three groups based on the serum luteinizing hormone to follicle-stimulating hormone (LH/FSH) ratio in the early follicular phase group 1 (LH/FSH 2.0), and group 3 (LH/FSH ≥2.0). The correlations between the LH/FSH ratio and various metabolic parameters were evaluated using Pearson correlation coefficients.RESULTS:
Patients with higher LH/FSH ratios showed higher total antral follicle counts and higher total ovarian volume. In the comparison of anthropometric and biochemical parameters among the three groups, the waist to hip ratio was the only parameter that differed significantly among the groups (P=0.003). Correlation analysis revealed no significant correlations between serum LH/FSH ratios and biochemical parameters related to insulin resistance. However, after adjustments for age and body mass index, a significant correlation between total cholesterol level and serum LH/FSH ratio was observed (r=0.221, P=0.018).CONCLUSION:
Most parameters related to insulin resistance, with the exception of total cholesterol level, are unrelated to the inappropriate pattern of serum gonadotropin secretion in Korean women with PCOS.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Síndrome do Ovário Policístico
/
Resistência à Insulina
/
Hormônio Luteinizante
/
Índice de Massa Corporal
/
Colesterol
/
Estudos Retrospectivos
/
Consenso
/
Relação Cintura-Quadril
/
Fase Folicular
/
Hormônio Foliculoestimulante
Tipo de estudo:
Guia de Prática Clínica
/
Estudo observacional
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Obstetrics & Gynecology Science
Ano de publicação:
2016
Tipo de documento:
Artigo
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