Research progress on the genetic etiology and treatment of nonobstructive azoospermia / 现代泌尿外科杂志
Journal of Modern Urology
;
(12): 911-915, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-1005983
ABSTRACT
Nonobstructive azoospermia (NOA) is a disease with complex etiology, genetic heterogeneity and phenotypic heterogeneity caused by multiple factors, including chromosome abnormalities, Y chromosome microdeletions, gene mutations and epigenetic modifications. At present, there is no unified and effective treatment strategy to restore spermatogenesis. The current treatment options include preoperative hormone optimization therapy, changing the testicular spermatogenesis microenvironment, and stem cell therapy. This article reviews the existing genetic etiology of NOA and related treatment methods, in order to provide reference for the clinical treatment.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Modern Urology
Ano de publicação:
2023
Tipo de documento:
Artigo
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