Application of decellularization-recellularization technique in plastic and reconstructive surgery / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 2017-2027, 2023.
Article
em En
| WPRIM
| ID: wpr-1007524
Biblioteca responsável:
WPRO
ABSTRACT
In the field of plastic and reconstructive surgery, the loss of organs or tissues caused by diseases or injuries has resulted in challenges, such as donor shortage and immunosuppression. In recent years, with the development of regenerative medicine, the decellularization-recellularization strategy seems to be a promising and attractive method to resolve these difficulties. The decellularized extracellular matrix contains no cells and genetic materials, while retaining the complex ultrastructure, and it can be used as a scaffold for cell seeding and subsequent transplantation, thereby promoting the regeneration of diseased or damaged tissues and organs. This review provided an overview of decellularization-recellularization technique, and mainly concentrated on the application of decellularization-recellularization technique in the field of plastic and reconstructive surgery, including the remodeling of skin, nose, ears, face, and limbs. Finally, we proposed the challenges in and the direction of future development of decellularization-recellularization technique in plastic surgery.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Cirurgia Plástica
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Engenharia Tecidual
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Medicina Regenerativa
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Matriz Extracelular
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Alicerces Teciduais
Idioma:
En
Revista:
Chinese Medical Journal
Ano de publicação:
2023
Tipo de documento:
Article