Progress on the mechanism and treatment of Parkinson's disease-related pathological pain / 生理学报
Acta Physiologica Sinica
; (6): 595-603, 2023.
Article
em Zh
| WPRIM
| ID: wpr-1007775
Biblioteca responsável:
WPRO
ABSTRACT
Parkinson's disease (PD) is a common neurodegenerative disease characterized by motor symptoms, including bradykinesia, resting tremor, and progressive rigidity. More recently, non-motor symptoms of PD, such as pain, depression and anxiety, and autonomic dysfunction, have attracted increasing attention from scientists and clinicians. As one of non-motor symptoms, pain has high prevalence and early onset feature. Because the mechanism of PD-related pathological pain is unclear, the clinical therapy for treating PD-related pathological pain is very limited, with a focus on relieving the symptoms. This paper reviewed the clinical features, pathogenesis, and therapeutic strategies of PD-related pathological pain and discussed the mechanism of the chronicity of PD-related pathological pain, hoping to provide useful data for the study of drugs and clinical intervention for PD-related pathological pain.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Ansiedade
/
Dor
/
Doença de Parkinson
/
Doenças do Sistema Nervoso Autônomo
/
Doenças Neurodegenerativas
Limite:
Humans
Idioma:
Zh
Revista:
Acta Physiologica Sinica
Ano de publicação:
2023
Tipo de documento:
Article