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Research Progress in the Regulation of Follicle Development by Melatonin / 中国医学科学院学报
Acta Academiae Medicinae Sinicae ; (6): 997-1004, 2023.
Artigo em Chinês | WPRIM | ID: wpr-1008158
ABSTRACT
Melatonin,an endocrine hormone synthesized by the pineal gland,plays an important role in the reproduction.The growth and development of follicles is the basis of female mammalian fertility.Follicles have a high concentration of melatonin.Melatonin receptors exist on ovarian granulosa cells,follicle cells,and oocytes.It regulates the growth and development of these cells and the maturation and atresia of follicles,affecting female fertility.This paper reviews the protective effects and regulatory mechanisms of melatonin on the development of ovarian follicles,granulosa cells,and oocytes and makes an outlook on the therapeutic potential of melatonin for ovarian injury,underpinning the clinical application of melatonin in the future.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Oócitos / Folículo Ovariano / Células da Granulosa / Mamíferos / Melatonina Limite: Animais Idioma: Chinês Revista: Acta Academiae Medicinae Sinicae Ano de publicação: 2023 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Oócitos / Folículo Ovariano / Células da Granulosa / Mamíferos / Melatonina Limite: Animais Idioma: Chinês Revista: Acta Academiae Medicinae Sinicae Ano de publicação: 2023 Tipo de documento: Artigo