Evaluation of the Usefulness of Kobias HBsAg and Anti-HBs / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
; : 411-414, 2003.
Article
em Ko
| WPRIM
| ID: wpr-100935
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: The analysis of serological markers for hepatitis B virus (HBV) is a useful tool for the prevention and diagnosis of HBV infection. In this work, we evaluated a newly improved domestic rapid assay, Kobias HBsAg and anti-HBs Window kits (Kobias, Korea) for the detection of HBsAg and anti-HBs in serum. METHODS: A total of 360 sera screened by enzyme immunoassay (EIA) (Enzygnost, DADE Behring, Germany) were included in this study. Each specimen was tested for HBsAg and anti-HBs by Kobias Window kits and Genedia Rapid device (Green Cross, Korea), conventional one step test kits. The results were compared with those of EIA. RESULTS: The sensitivity and specificity of Kobias HBsAg were 99.2% and 96.7%, and those of Kobias Anti-HBs were 95.8% and 96.7%, respectively. The concordance rates between EIA and Kobias HBsAg and Kobias Anti-HBs were 98.3% and 96.1%, and those between Kobias kits and Genedia kits for HBsAg and anti-HBs were 97.8% and 93.9%, respectively. CONCLUSIONS: Kobias HBsAg/Anti-HBs kits are simple, rapid, and low-cost methods for detecting HBsAg and anti-HBs. With comparable results with EIA, the Kobias HBsAg/Anti-HBs kits could be suitable for screening purposes or in emergency situations.
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WPRIM
Assunto principal:
Vírus da Hepatite B
/
Programas de Rastreamento
/
Técnicas Imunoenzimáticas
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Sensibilidade e Especificidade
/
Diagnóstico
/
Emergências
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Teste de Esforço
/
Antígenos de Superfície da Hepatite B
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
Ko
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2003
Tipo de documento:
Article