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Effect of prolactin on penile erection: a cross-sectional study / 亚洲男科学杂志(英文版)
Asian Journal of Andrology ; (6): 587-591, 2019.
Artigo em Inglês | WPRIM | ID: wpr-1009729
ABSTRACT
Although elevated prolactin levels have been shown to inhibit penile erection, the relationship between prolactin and erection of the penile tip or base has not been extensively researched. We therefore investigated the prolactin's effects on erection of the penile tip and base, with a cross-sectional study of 135 patients with erectile dysfunction, based on scores of ≤21 on the International Index of Erectile Function-5. All patients were tested for nocturnal penile tumescence, blood pressure, serum glucose, total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, luteinizing hormone, follicle-stimulating hormone, prolactin, estradiol, testosterone, and progesterone. Univariate and multivariate analyses were used to assess the associations between prolactin levels and erection at the penile tip and base. We found no obvious relationship between erection time at penile tip and prolactin levels, but observed a negative correlation between base erection time and prolactin level (hazard ratio -2.68; 95% confidence interval [CI] -5.13--0.22). With increasing prolactin concentration, multivariate analysis showed obvious reduction in base erection time among patients with normal Rigiscan results (hazard ratio -3.10; 95% CI -7.96-1.77; P < 0.05). Our data indicate that prolactin inhibits penile erection, particularly at the penile base. In addition, when the effective erection time of the penile base lasts longer than 10 min, prolactin has a more obvious inhibitory effect on penile base erection.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prolactina / Fatores de Tempo / Ereção Peniana / Estudos Transversais / Disfunção Erétil Limite: Adulto / Humanos / Masculino Idioma: Inglês Revista: Asian Journal of Andrology Ano de publicação: 2019 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prolactina / Fatores de Tempo / Ereção Peniana / Estudos Transversais / Disfunção Erétil Limite: Adulto / Humanos / Masculino Idioma: Inglês Revista: Asian Journal of Andrology Ano de publicação: 2019 Tipo de documento: Artigo