Role of cytoplasmic lncRNAs in regulating cancer signaling pathways / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
;
(12): 1-8, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-1010438
ABSTRACT
Cancer remains a serious healthcare problem despite significant improvements in early detection and treatment approaches in the past few decades. Novel biomarkers for diagnosis and therapeutic strategies are urgently needed. In recent years, long noncoding RNAs (lncRNAs) have been reported to be aberrantly expressed in tumors and show crosstalk with key cancer-related signaling pathways. In this review, we summarized the current progress of research on cytoplasmic lncRNAs and their roles in regulating cancer signaling and tumor progression, further characterization of which may lead to effective approaches for cancer prevention and therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transdução de Sinais
/
Biomarcadores Tumorais
/
Proteínas Serina-Treonina Quinases
/
Fosfatidilinositol 3-Quinases
/
Citoplasma
/
Proteínas Proto-Oncogênicas c-akt
/
Subunidade alfa do Fator 1 Induzível por Hipóxia
/
RNA Longo não Codificante
/
Via de Sinalização Hippo
/
Neoplasias
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Journal of Zhejiang University. Science. B
Ano de publicação:
2019
Tipo de documento:
Artigo
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