Lymphomatoid gastropathy: one case report and literatures review / 中华血液学杂志
Chinese Journal of Hematology
; (12): 937-941, 2018.
Article
em Zh
| WPRIM
| ID: wpr-1011892
Biblioteca responsável:
WPRO
ABSTRACT
Objective: To report the first case of lymphomatoid gastropathy in China, and to demonstrate the clinical characteristics, diagnostic approach, treatment and prognosis in this kind of patients. Methods: One patient was diagnosed as lymphomatoid gastropathy at Peking Union Medical College Hospital, and her clinical characteristics, lab data, treatment and follow-up outcomes were reviewed. Results: A case of a 51-year-old female was presented, who underwent esophagogastroduodenoscopy (EGD) due to slight epigastric discomfort. EGD revealed multiple ulcers and erosions. Biopsies showed atypical lymphocytes infiltration with CD3(+), CD56(+), CD20(-), CD8(-), TIA(+), Granzyme B(-) and Ki-67 (75%). Epstein-Barr virus-encoded RNA in situ hybridization was negative. Four months later, repeated EGD examination showed regression of the lesions without specific treatment. Conclusion: Lymphomatoid gastropathy was a unique disease entity mimicking NK/T-cell lymphomas in pathology, with the quite different profile of treatment and prognosis. It's important to consider this issue during the differential diagnosis to avoid any excessive treatment.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Gastropatias
/
Biópsia
/
China
/
Imunofenotipagem
/
Linfoma de Células T Periférico
/
Hibridização In Situ
/
Doenças Linfáticas
Limite:
Female
/
Humans
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Hematology
Ano de publicação:
2018
Tipo de documento:
Article