Advances in mechanism of methotrexate on toxicity in various organs / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 213-218, 2024.
Article
em Zh
| WPRIM
| ID: wpr-1013583
Biblioteca responsável:
WPRO
ABSTRACT
As a widely used anti-tumor drug and anti-rheumatic drug in clinic, methotrexate (MTX) has many toxic and side effects, including gastrointestinal mucosa injury, central nervous system injury, liver and kidney function injury, etc. They often bring great trouble to the follow-up treatment of patients. The clarification of the mechanism of MTX toxicity to various organs has become the key to rescue the toxicity. The purpose of the article is to review the toxicity mechanism of MTX in various organs, so as to save the patients from the adverse reactions in clinical treatment.
Texto completo:
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2024
Tipo de documento:
Article