Calpain-1 accelerates endothelial cell apoptosis in pulmonary hypertension by inducing endoplasmic reticulum stress / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 723-730, 2023.
Article
em Zh
| WPRIM
| ID: wpr-1013903
Biblioteca responsável:
WPRO
ABSTRACT
Aim To explore the mechanism by which calpain-1 promotes hypoxia-induced pulmonary hypertension pulmonary artery endothelial cell apoptosis through endoplasmic reticulum stress. Methods C57BL/6 wild-type (WT) and calpain-1 gene knockout mice (KO) were reared in a hypoxic chamber (10% O
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2023
Tipo de documento:
Article