The therapeutic effect of salidroside on rats with permanent cerebral ischemia through regulating PDK/Akt signaling pathway / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 698-703, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-1014421
ABSTRACT
Aim To investigate the neuroprotective effect and mechanism of salidroside (Sal) on rats with permanent middle cerebral artery occlusion model (pMCAO) by regulating the PI3 K/AKT signaling pathway. Methods A total of 80 healthy adult SPF male SD rats were randomly divided into sham operation group (sham group), model group (pMCAO group), drug administration group (pMCAO + Sal group) and inhibitor group (pMCAO + Sal + YL group). After the pMCAO model rats were prepared by the line bolt method, salidroside (50 mg · kg
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2021
Tipo de documento:
Artigo
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