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Hederagenin improves psoriasis skin lesions by inhibiting macrophage mincle-mediated inflammation / 中国临床药理学与治疗学
Chinese Journal of Clinical Pharmacology and Therapeutics ; (12): 1339-1346, 2023.
Artigo em Chinês | WPRIM | ID: wpr-1014585
ABSTRACT

AIM:

To observe the effects and mechanisms of hederagenin (HDG) in improving psoriasis skin lesions and inflammation in mice.

METHODS:

A mouse model of psoriasis was established by depilation of the back and continuous application of imiquimod for 7 days in C57 mice. After modeling, HDG was administered orally (low dose 25 mg · kg

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Clinical Pharmacology and Therapeutics Ano de publicação: 2023 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Clinical Pharmacology and Therapeutics Ano de publicação: 2023 Tipo de documento: Artigo