Role of ataxia-telangiectasia mutated gene in maintaining quiescence of neural stem cell from subgranular zone of mouse hippocampus / 解剖学报
Acta Anatomica Sinica
; (6): 545-550, 2022.
Article
em Zh
| WPRIM
| ID: wpr-1015291
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the role of ataxia-telangiectasia mutated gene (ATM) in maintaining quiescence of neural stem cells (NSCs) from subgranular zone (SGZ) of hippocampal dentate gyms in mice. Methods We constructed 1-month-old and 4-month-old mice ATM knockout mice, with 12 mice in each group. The NSCs in SGZ of ATM knockout mice were isolated, cultured and identified in vitro. The proliferation ability of NSCs in SGZ of 1-month-old ATM
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Índice:
WPRIM
Idioma:
Zh
Revista:
Acta Anatomica Sinica
Ano de publicação:
2022
Tipo de documento:
Article