Progress of Research on Application of Antispasmodics in Digestive Endoscopy / 胃肠病学

ABSTRACT

Reasonable use of antispasmodics to attenuate gastrointestinal peristalsis during digestive endoscopy is an effective clinical strategy to improve the clarity of endoscopic images and diagnostic accuracy. The commonly used antispasmodics in gastroenteroscopy mainly include systemic antispasmodics and local antispasmodics at present. Systemic antispasmodics have some limitations, such as inconvenience in usage, many contraindications and adverse reactions. Local antispasmodics can act directly on the digestive tract mucosa by oral administration or spraying, which can quickly and effectively inhibit peristalsis, and is convenient for clinical use with fewer adverse reactions. This review summarizes the mechanism of action, efficacy and application of systemic antispasmodics and local antispasmodics in digestive endoscopy, in order to provide strategies for the selection of antispasmodics in digestive endoscopy.