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Comparison of Extended-Spectrum beta-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Bloodstream Infection Epidemiology / 병원감염관리
Korean Journal of Nosocomial Infection Control ; : 45-51, 2014.
Artigo em Coreano | WPRIM | ID: wpr-10186
ABSTRACT

BACKGROUND:

Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae are main pathogens of bloodstream infection. We compared the epidemiology of ESBL-producing E. coli and K. pneumoniae.

METHODS:

From January 2003 through March 2007, we retrospectively investigated the clinical characteristics and comorbidities of patients with bloodstream infection by ESBL-producing E. coli and K. pneumoniae.

RESULTS:

During the study period, 79 patients (54 with E. coli and 25 with K. pneumoniae) with blood cultures positive for ESBL-producing E. coli or K. pneumoniae were studied. When comparing the source of bloodstream infections, urinary tract infections (UTIs) were more commonly caused by E. coli (24% vs. 0; P=0.007), and respiratory tract and soft tissue infection (36% vs. 15%; P=0.04, 12% vs. 0; P=0.03, respectively) were more commonly associated with K. pneumoniae. Among hospital-acquired bloodstream infection, third-generation cephalosporin was more commonly used in patients with E. coli than patients with K. pneumoniae (81% vs. 24%, P<0.001). Medical devices (central venous catheter and urinary catheter) were more commonly used in patients with K. pneumoniae.

CONCLUSION:

ESBL-producing E. coli bloodstream infection is more common in urinary tract infections. ESBL-producing K. pneumoniae is more common in respiratory tract infections and in skin and soft tissue infections. In hospital-acquired infections, ESBL-producing E. coli bloodstream infection is more common in biliary tract infection. ESBL-producing E. coli was more commonly associated with prior frequent antibiotics use and K. pneumoniae was more commonly associated with use of medical devices.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pneumonia / Sistema Respiratório / Infecções Respiratórias / Pele / Infecções Urinárias / Beta-Lactamases / Sistema Biliar / Comorbidade / Epidemiologia / Estudos Retrospectivos Tipo de estudo: Estudo observacional / Estudo de rastreamento Limite: Humanos Idioma: Coreano Revista: Korean Journal of Nosocomial Infection Control Ano de publicação: 2014 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pneumonia / Sistema Respiratório / Infecções Respiratórias / Pele / Infecções Urinárias / Beta-Lactamases / Sistema Biliar / Comorbidade / Epidemiologia / Estudos Retrospectivos Tipo de estudo: Estudo observacional / Estudo de rastreamento Limite: Humanos Idioma: Coreano Revista: Korean Journal of Nosocomial Infection Control Ano de publicação: 2014 Tipo de documento: Artigo