Effects of Paravertebral Block and Local Infiltration Anesthesia on Postoperative Inflammation Factor Level and Recovery Quality of Patients Undergoing Robot-assisted Radical Nephrectomy / 医学研究杂志

ABSTRACT

Objective To evaluate the effects of ultrasound-guided paravertebral nerve block(PVNB)and local infiltration anes-thesia on postoperative inflammation level and recovery quality of patients after robot-assisted radical nephrectomy.Methods A total of 100 patients who underwent elective robot-assisted laparoscopic radical nephrectomy in General Hospital of Central Theater Command from January 2022 to August 2022 were selected prospectively.They were randomly divided into observation group and control group by random number table method,with 50 cases in each group.The observation group chose general anesthesia combined with PVNB,while the control group chose general anesthesia combined with incision local infiltration anesthesia.All patients were connected with patient-controlled intravenous analgesia(PCIA)after operation.The pain visual analogue scale(VAS)of rest and cough,the systemic immune inflammatory index(SII),interleukin-6(IL-6),and the QoR-15 scores of the patients after operation in the two groups were recor-ded.The dosage of remifentanil,the times of effective compression of analgesia pump and remedial analgesia were recorded in the two groups.Adverse reactions and related complications were recorded.Results Compared with the control group,the pain VAS of rest and cough in the observation group were lower on first and second day after operation(P<0.05).SII and IL-6 were lower on the first and third day after operation(P<0.05).The QoR-15 scores on the first,second,and fifth day after operation were higher(P<0.05).The dosage of remifentanil was less during operation(P<0.01).The effective pressing times of intravenous analgesia pump were less af-ter operation(P<0.05).Lower incidence of remedial analgesia and adverse effects(P>0.05).Conclusion Compared with local in-filtration anesthesia,PVNB can provide better intraoperative and postoperative analgesia effect,reduce the early postoperative inflammato-ry reaction and accelerate the early recovery of patients for robot-assisted radical nephrectomy.