A Hepatic Epithelioid Hemangioendothelioma Treated by Living Donor Liver Transplantation

ABSTRACT

Hepatic epithelioid hemangioendothelioma (HEHE) is a rare a lowgrade malignant tumor of endothelial origin. The natural history of this tumor is unpredictable and it is difficult to differentiate from cholangiocarcinoma or metastatic liver tumor on imaging study. A case of HEHE treated by living donor liver transplantation (LDLT) is presented. A 52-year-old man was admitted because of multiple bilobar liver masses. The histological appearances of the preoperative biopsy showed positive immunostaining for factor VIII and CD34 antigens. So it was dagrored as HEHE The tumor was unresectable because of multiple involvement of both lobes of the liver. The tumor was enlarged after 3months, which prompted the decision to perform LDLT. The right liver of the donor was transplanted to the recipient. The intraoperative & postoperative courses were uneventful. At the time of writing, the patient had survived for 13 months without any complications.