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A Hydroxyurea-induced Leg Ulcer
Annals of Dermatology ; : 39-41, 2009.
Artigo em Inglês | WPRIM | ID: wpr-103069
ABSTRACT
Hydroxyurea is a cytostatic agent that has recently become the drug of choice in the treatment of various myeloproliferative diseases. The cutaneous side effects of hydroxyurea include xerosis, hyperpigmentation, nail discoloration, and scaling. Leg ulcers have only rarely been reported in association with hydroxyurea treatment. A 75-year-old woman presented with leg ulcers, nail discoloration, and xerosis. The leg ulcers were refractory to conventional treatment. She had been taking oral hydroxyurea since being diagnosed with essential thrombocytosis in 2002. Hence, we suspected hydroxyurea-induced leg ulcers and discontinued her hydroxyurea treatment; the ulcers gradually healed thereafter. We present a rare case of hydroxyurea-induced leg ulcers in Korea.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Robenidina / Trombocitose / Úlcera / Hiperpigmentação / Hidroxiureia / Coreia (Geográfico) / Perna (Membro) / Úlcera da Perna / Unhas Limite: Idoso / Feminino / Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Annals of Dermatology Ano de publicação: 2009 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Robenidina / Trombocitose / Úlcera / Hiperpigmentação / Hidroxiureia / Coreia (Geográfico) / Perna (Membro) / Úlcera da Perna / Unhas Limite: Idoso / Feminino / Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Annals of Dermatology Ano de publicação: 2009 Tipo de documento: Artigo