Chemoprevention of Gastric Cancer: Helicobacter pylori Eradication
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
;
: 166-168, 2017.
Artigo
em Coreano
| WPRIM
| ID: wpr-103586
ABSTRACT
Gastric cancer is one of the most common fatal malignancies in the world, with a high incidence in Korea and Japan. Helicobacter pylori infection is an important factor in the pathogenesis of gastric cancer. Epidemiological studies have shown a strong causal relationship between H. pylori infection and gastric cancer. Animal studies have also shown that eradication of H. pylori infection, especially at the early stage, is effective in preventing H. pylori-related gastric carcinogenesis. H. pylori eradication leads to regression and prevents the progression of gastric precancerous lesions but only in a minority of cases. H. pylori eradication appears to be the most promising approach for gastric cancer prevention. The current available data from human studies show that H. pylori eradication can reduce the risk of developing gastric cancer, and this strategy is more useful in patients without atrophic gastritis or intestinal metaplasia. A longer follow-up and additional studies are needed for a better understanding of this issue.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Gástricas
/
Estudos Epidemiológicos
/
Incidência
/
Seguimentos
/
Helicobacter pylori
/
Helicobacter
/
Quimioprevenção
/
Carcinogênese
/
Gastrite Atrófica
/
Japão
Tipo de estudo:
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
Limite:
Animais
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Ano de publicação:
2017
Tipo de documento:
Artigo
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