False Susceptibility to Imipenem by Vitek GPS Card in Enterococcus faecium / 임상검사와정도관리
Journal of Laboratory Medicine and Quality Assurance
;
: 211-214, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-103622
ABSTRACT
BACKGROUND:
Enterococcus faecium (E. faecium) is potential pathogens of mixed infections for which a broad-spectrum antimicrobial agents such as imipenem has a therapeutic role. But controversy continues concerning testing imipenem versus enterococci. The purpose of this study were 1) to investigate the ability of penicillin and ampicillin minimum inhibitory concentration (MIC) to predict in vitro susceptibility of E. faecium versus imipenem. and 2) to compare MICs of ampicillin, penicillin and imipenem by the Vitek system with those by agar dilution method.METHODS:
Fifty-two isolates of E. faecium between April 2002 and May 2002 were tested. Each isolate was tested versus penicillin, ampicillin and imipenem. MICs were determined by Vitek system and agar dilution method according to NCCLS guidelines. Imipenem MIC determinations were repeated by E-test.RESULTS:
MIC of Vitek system tends to be lower than that of agar dilution method, but there was good concordance between MICs of penicillin and ampicillin by Vitek system and agar dilution method. But for imipenem, the MICs by the agar dilution method did not correspond with the Vitek results. Of the 52 E. faecium isolates tested, in vitro activity of penicillin and ampicillin accurately predicts that of imipenem.CONCLUSIONS:
MICs of ampicillin and penicillin are reliable, but imipenem MIC is not reliable for E. faecium by Vitek system. In vitro activity of penicillin and ampicillin versus E. faecium accurately predicts that of imipenem.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Penicilinas
/
Testes de Sensibilidade Microbiana
/
Imipenem
/
Enterococcus faecium
/
Enterococcus
/
Ágar
/
Coinfecção
/
Ampicilina
/
Anti-Infecciosos
Tipo de estudo:
Guia de Prática Clínica
Idioma:
Coreano
Revista:
Journal of Laboratory Medicine and Quality Assurance
Ano de publicação:
2003
Tipo de documento:
Artigo
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