Clinical efficacy,SAS and HAMD scale scores and 5-HT level of patients with post-stroke depression treated by awakening The Mind and opening the qi needle / 中风与神经疾病杂志

ABSTRACT

@#Objective　To explore the clinical effect,SAS and HAMD scale score and 5-HT level of patients with post-stroke depression treated by awakening the mind and opening the qi needle.Methods　A total of 93 patients with poststroke depression were included in the study,all of whom were admitted to our hospital from September 2018 to October 2020.Patients were divided into the control group and the observation group by random number table method.Patients in the control group (46 cases) were given conventional western medicine treatment.We compared between two groups of patients before and after treatment,treatment of depression self-rating scale (SDS) and Hamilton depression scale (HAMD) score changes,serotonin (5-HT) level change and neural function defect scale (NHISS) score and active ability of daily life (ADL) scale,simple mental state examination (MMSE) score changes,serum interleukin 6 (IL-6),interleukin 8 (IL-8),tumor necrosis factor alpha (TNF alpha) level changes,adverse reaction conditions.Results　The total effective rate (95.74%) in the observation group was higher than that in the control group (82.61%)(P<0.05).Before the treatment,two groups of patients with SDS,HAMD,5-HT,NHISS,ADL,MMSE,IL-6,IL-8 and TNF alpha index comparison(P>0.05),groups of patients after treatment,HAMD,SDS 5-HT,NHISS,ADL,MMSE,IL-6,IL-8,TNF alpha indexes are improved,such as observation group after treatment in patients with SDS,HAMD,5-HT,NHISS,ADL,MMSE,IL-6,IL-8 and TNF alpha indicators are superior to control group(P<0.05).The adverse reaction rate in the observation group (2.13%) was lower than that in the control group (15.22%)(P<0.05).Conclusion　The method of “awakening the mind and opening the depression” has a significant clinical effect on post-stroke depression.The patients’ depressive symptoms are improved and the recovery is good.Meanwhile,it can also reduce the side effects of medication in patients.