Renal Hypoperfusion Associated with Splenorenal Shunts in Liver Cirrhosis
Journal of the Korean Radiological Society
;
: 409-416, 2008.
Artigo
em Inglês
| WPRIM
| ID: wpr-104421
ABSTRACT
PURPOSE:
To determine whether spontaneous a splenorenal shunt can be used as an imaging predictor of early renal hemodynamic changes in patients with cirrhosis. MATERIALS ANDMETHODS:
The study included 82 cirrhotic patients and 41 control subjects. Three-phase CT was performed and CT attenuation values (Hounsfield units) of the renal cortex in three phases were measured to evaluate renal perfusion. Likelihood ratio tests for trend were conducted for age, presence of ascites, and Child's grade.RESULTS:
The mean CT attenuation values of the renal cortex in cirrhotic patients were significantly lower than the values of control subjects in three phases 153.3 +/- 37.9 versus 173.3 +/-25.2 in the arterial phase, 172.6 +/- 41.0 versus 197.6 +/- 26.5 in the portal phase and 136.9 +/- 26.0 versus 152.7 +/- 20.0 in the delayed phase, respectively. The mean CT attenuation value of cortices in patients with renal hypoperfusion was 119.9 +/- 11.8 in the portal phase. Child's class C (aOR 58.4, 95% CI 3.6-956.2; p < 0.01) and the presence of a renal shunt (aOR 7.5, 95% CI 1.8-30.5; p < 0.01) were associated with renal hypoperfusion. The incidence of renal hypoperfusion was associated with Child's grade (trend p < 0.01), and not with the grade of ascites or age.CONCLUSION:
A dilated spontaneous splenorenal shunt may be a risk factor for renal hypoperfusion in cirrhosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Perfusão
/
Ascite
/
Fibrose
/
Derivação Esplenorrenal Cirúrgica
/
Incidência
/
Fatores de Risco
/
Hemodinâmica
/
Fígado
/
Cirrose Hepática
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of the Korean Radiological Society
Ano de publicação:
2008
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS