Impact of an Antimicrobial Stewardship Program on Unnecessary Double Anaerobic Coverage Prescription / 감염과화학요법
Infection and Chemotherapy
;
: 111-116, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-104518
ABSTRACT
BACKGROUND:
Co-administration of two or more antimicrobials with anti-anaerobic activity is not recommended except in certain circumstances. We therefore conducted an intervention to reduce unnecessary double anaerobic coverage (DAC) prescription. MATERIALS ANDMETHODS:
The intervention consisted of education using an institutional intranet and prospective audits and feedback provided through collaboration between a pharmacist and an infectious diseases physician in Seoul National University Bundang Hospital, a tertiary hospital in Seongnam, Republic of Korea, in 2013. The study period was 1 year which contained 6 months of pre-intervention period and 6 months of intervention period. To estimate the overall effect of the intervention, we compared the monthly number of patients receiving unnecessary DAC for more than 3 days and the proportion of patients receiving unnecessary DAC for more than 3 days among all patients receiving DAC.RESULTS:
The average monthly number of patients receiving unnecessary DAC for more than 3 days after screening decreased by 73.9% in the intervention period from 26.8 to 7.0. Wilcoxon rank sum test revealed there was a significant statistical difference in the monthly number of patients receiving unnecessary DAC for more than 3 days (P = 0.005). The proportion of patients receiving unnecessary DAC for more than 3 days after screening among all patients identified as receiving necessary or unnecessary DAC also decreased by 67.8% in the intervention period from 42.3% to 13.6% (P < 0.001).CONCLUSION:
The multidisciplinary antimicrobial stewardship program with combined methods reduced unnecessary DAC prescription successfully.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacêuticos
/
Bactérias Anaeróbias
/
Redes de Comunicação de Computadores
/
Programas de Rastreamento
/
Doenças Transmissíveis
/
Comportamento Cooperativo
/
Educação
/
Prescrições
/
República da Coreia
/
Prescrição Inadequada
Tipo de estudo:
Estudo de rastreamento
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Infection and Chemotherapy
Ano de publicação:
2015
Tipo de documento:
Artigo
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