Effects of one-time and two-time intra-articular injection of hyaluronic acid sodium salt after joint surgery in dogs
Journal of Veterinary Science
;
: 215-222, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-104696
ABSTRACT
Thirty-one dogs with patellar luxation (grades 2 and 3) were categorized into three groups. Group 1 (G.1; n = 12) had sodium hyaluronate (SHA) intra-articularly injected into the stifle joint that received surgery. Group 2 (G.2; n = 10) received SHA twice first after surgery and then 1 week later. Group 3 (G.3; n = 9) served as a control, without injection. Blood was collected before injection and then once a week for 4 weeks after injection for evaluation of chondroitin sulfate (CS-WF6) and hyaluronan (HA). The results revealed significantly (p 0.05) was observed in serum biomarkers between G.1 and G.2. In conclusion, intra-articular injection with SHA after joint surgery may improve homeostasis of the joint, retarding the process of OA.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Joelho de Quadrúpedes
/
Análise Química do Sangue
/
Ensaio de Imunoadsorção Enzimática
/
Sulfatos de Condroitina
/
Osteoartrite do Joelho
/
Relação Dose-Resposta a Droga
/
Viscossuplementos
/
Ácido Hialurônico
/
Injeções Intra-Articulares
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2013
Tipo de documento:
Artigo
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