Cloning a new allele form of bovine TNF-alpha
Journal of Veterinary Science
;
: 139-141, 2001.
Artigo
em Inglês
| WPRIM
| ID: wpr-104742
ABSTRACT
Although little is known on the function of gammadelta T lymphocytes, there is increasing evidence that gammadelta T lymphocytes are early responders and modulators of immune responses against pathogens and cytokines such as IL-2, IL-7, IL-15 and TNF-alpha. To study the role TNF-alpha on gammadelta T lymphocytes, we cloned bovine TNF-alpha. Sequence analysis revealed that a new allele form of bovine TNF-alpha was cloned which has 3 additional nucleotide sequences as well as 3 nucleotide substitutions compared with previously reported bovine TNF-alpha. Further studies are needed to document the functional significance of a new allele form of TNF-alpha in cattle.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dados de Sequência Molecular
/
Sequência de Bases
/
Linfócitos T
/
Biblioteca Gênica
/
Alinhamento de Sequência
/
Sequência de Aminoácidos
/
Fator de Necrose Tumoral alfa
/
Receptores de Antígenos de Linfócitos T gama-delta
/
Clonagem Molecular
/
Alelos
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2001
Tipo de documento:
Artigo
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