Histomorphometric evaluation of bone healing with natural calcium carbonatederived bone substitutes in rat calvarial defect / 대한치주과학회지
The Journal of the Korean Academy of Periodontology
;
: 83-90, 2008.
Artigo
em Coreano
| WPRIM
| ID: wpr-105075
ABSTRACT
PURPOSE:
This study investigated the osteoconductivity of natural calcium carbonate-derived bone substitutes, hen eggshell (ES), and compared with those of commercial bone substitutes. MATERIALS ANDMETHODS:
Osseous defects created in the rat calvaria were filled with particulated ES(ES-1), ES with calcium-deficient hydroxyapatite surface layer (ES-2), Biocoral(Inoteb, France), and Bio-Oss(Geistlich Pharma, Wolhusen, Switzerland). After 4 and 8 weeks of healing, histomorphometic analysis was performed to evaluate the amount of newly formed mineralized bone area (NB%).RESULTS:
Histologic and histomorphometric analysis showed new bone formation and direct bony contact with the grafted materials in all groups. At 4 weeks, Biocoral group showed greater NB% compared to Bio-Oss and ES-1 groups (P<0.05). At 8 weeks, Biocoral and ES-2 groups showed significantly greater NB% compared to Bio-Oss group (P<0.05).CONCLUSION:
These results indicate that natural calcium carbonate-derived bone substitutes with microporous calciumdeficient hydroxyapatite surface layer may be an effective materials treating osseous defects.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteogênese
/
Crânio
/
Carbonato de Cálcio
/
Cálcio
/
Durapatita
/
Substitutos Ósseos
/
Transplantes
/
Minerais
Limite:
Animais
Idioma:
Coreano
Revista:
The Journal of the Korean Academy of Periodontology
Ano de publicação:
2008
Tipo de documento:
Artigo
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