A Case of Acute Generalized Exanthematous Pustulosis / 대한피부과학회지

ABSTRACT

Acute generalized exanthematous pustulosis (AGEP) is initially termed by Beylot to describe a disease entity with sudden onset of amicrobial pustular eruption accompanied with fever and leukocytosis. A 58-year-old man presented with sudden onset of multiple, generally pinhead sized pustules on erythematous base scattered on trunk accompanied with fever. The patient had been on medication of cefotiam prior to skin eruption for 4 days after esophageal cancer operation. Histopathological study of a skin biopsy specimen revealed subcorneal pustules with a few neutrophils and few eosinophils in dermis. After discontinuation of cefotiam and systemic steroid medication for 5 days, the eruption resolved clearly without scars within 4 days.