Whole blood versus serum ionized calcium concentrations in dialysis patients
The Korean Journal of Internal Medicine
;
: 226-230, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-105989
ABSTRACT
BACKGROUND/AIMS:
The aim of this study is to measure the difference of ionized calcium between heparinized whole blood and serum.METHODS:
We recruited 107 maintenance hemodialysis (HD) patients from our hospital HD unit. The clinical and laboratory data included ionized calcium in serum and in whole blood (reference, 4.07 to 5.17 mg/dL).RESULTS:
The level of ionized calcium in serum was higher than that in whole blood (p < 0.001). Bland-Altman analysis showed that difference for ionized calcium was 0.5027. For the difference, the nonstandardized beta was -0.4389 (p < 0.001) and the intercept was 2.2418 (p < 0.001). There was a significant difference in the distribution of categories of ionized calcium level between two methods (kappa, 0.279; p < 0.001).CONCLUSIONS:
This study demonstrates that whole blood ionized calcium is underestimated compared with serum ionized calcium. Positive difference increases as whole blood ionized calcium decreases. Therefore, significant hypocalcemia in whole blood ionized calcium should be verified by serum ionized calcium.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Manejo de Espécimes
/
Biomarcadores
/
Cálcio
/
Valor Preditivo dos Testes
/
Reprodutibilidade dos Testes
/
Diálise Renal
/
Hipercalcemia
/
Hipocalcemia
/
Nefropatias
Tipo de estudo:
Estudo prognóstico
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
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