Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis
The Korean Journal of Internal Medicine
;
: 1-5, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-106143
ABSTRACT
Systemic sclerosis is a connective tissue disease characterized by alterations in microvascular structure and function. In these patients, numerous studies have demonstrated a relationship between capillary morphology and peripheral blood perfusion. Nailfold videocapillaroscopy reveals the peripheral microvascular morphology and thus allows classification and scoring of capillary abnormalities with respect to different microangiopathy patterns (early, active, and late). Laser Doppler flowmetry and laser speckle contrast analysis can be used to estimate cutaneous blood flow through microvessels and to assess and quantify blood perfusion at peripheral sites. These two methods are also used to identify changes in digital blood perfusion after the infusion of vasodilators.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fluxo Sanguíneo Regional
/
Escleroderma Sistêmico
/
Pele
/
Vasodilatadores
/
Gravação em Vídeo
/
Velocidade do Fluxo Sanguíneo
/
Valor Preditivo dos Testes
/
Fluxometria por Laser-Doppler
/
Angioscopia Microscópica
/
Microvasos
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo
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