Primary Cutaneous Solitary Fibrous Tumor / 대한피부과학회지

ABSTRACT

A solitary fibrous tumor (SFT) is a relatively uncommon neoplasm that usually occurs in the pleura. However, SFTs are now known to affect various other anatomic sites as well, including rare examples in the skin. Cutaneous SFT is composed of uniformly spindled cells, which is classically described as a patternless feature. This tumor can mimic a variety of benign and malignant mesenchymal neoplasms. The first patient presented with a 3x3 cm sized subcutaneous nodule on the neck. Histopathologically, the biopsy specimen showed proliferation of spindle cells and epitheliod cells. Immunohistochemical stains for CD34, vimentin, bcl-2, and CD99 were strongly expressed. The second patient presented with a 1.5x1 cm sized subcutaneous nodule on the occipital area. The biopsy specimen was histopathologically consistent with SFT. Primary SFT developing on the skin is extremely rare, and only two cases have been reported in the Korean literature. SFT should be distinguished from primary spindle cell neoplasms of the skin.