A Case of Wegener's Granulomatosis with Central Nervous System Involvement Mimicking Lung Cancer with Brain Metastasis
Journal of Rheumatic Diseases
;
: 181-185, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-107354
ABSTRACT
Wegener's granulomatosis (WG) classically consists of necrotizing granulomatous inflammation of the upper and/or lower respiratory tract, necrotizing glomerulonephritis, and an autoimmune necrotizing systemic vasculitis affecting predominantly small vessels. We report a case of WG with central nervous system (CNS) involvement. WG is being diagnosed through pulmonary nodule biopsy. A small nodular lesion in the left posterior basal ganglia of brain being highly suspicious for granulomatosis was detected by MRI. After IV pulse cyclophosphamide and oral corticosteroid treatment for over 4 months, clinical manifestations and CNS lesions in brain MRI is improved. WG might have multiple granulomatous lesions which could be misdiagnosed due to malignancy. CNS involvement in WG is rare but careful evaluation is necessary when there are suspicious symptoms or lesions in CNS.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sistema Respiratório
/
Gânglios da Base
/
Biópsia
/
Encéfalo
/
Sistema Nervoso Central
/
Granulomatose com Poliangiite
/
Ciclofosfamida
/
Vasculite Sistêmica
/
Glomerulonefrite
/
Inflamação
Idioma:
Inglês
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2013
Tipo de documento:
Artigo
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