Interstitial Nephritis and IgA Nephropathy in a Patient with Acute Hepatitis A / 대한신장학회지

ABSTRACT

Hepatitis A is one of the most common infectious diseases. It is a self-limiting disease affecting the liver. Although extrahepatic manifestations are not common, a few cases associated with renal diseases have been reported. In those cases, patients presented with acute tubular necrosis, acute interstitial nephritis, IgA nephropathy, mesangioproliferative glomerulonephritis, etc. We here report a case of interstitial nephritis and IgA nephropathy associated with acute hepatitis A. A previously healthy 31-year old woman was admitted with an acute hepatitis A, which was confirmed by IgM anti-hepatitis A antibody. Acute renal failure was developed and hemodialysis was urgently required. The patient had acute interstitial nephritis and IgA nephropathy diagnosed by kidney biopsy. Liver and kidney functions gradually recovered their normal conditions.