Relationship among Alcohol Consumption, Facial Flushing Response and Dyslipidemia in Male
Korean Journal of Health Promotion
;
: 153-161, 2016.
Artigo
em Coreano
| WPRIM
| ID: wpr-108401
ABSTRACT
BACKGROUND:
Facial flushing response to drinking is observed in East Asians with deficient activity of the variant aldehyde dehydrogenase 2 genotype. This study examined the role of flushing response in the relationship between alcohol consumption and dyslipidemia.METHODS:
This cross-sectional study included 1,443 Korean men, including 261 non-drinkers, 470 flushers and 712 non-flushers. Based on a questionnaire, weekly alcohol consumption was assessed and categorized into 4 groups. Dyslipidemia was defined by the National Cholesterol Education Program-Adult Treatment Panel III criteria. After adjusting for confounding factors, we evaluated the relationship between weekly alcoholic drinks and dyslipidemia in flushers and non-flushers by comparing with non-drinkers, using a multi-variable logistic regression analysis.RESULTS:
Non-flushers had a significant relationship between hypertriglyceridemia and alcohol consumption in two groups (4-8 drinks adjusted odds ratio [aOR] 1.937, 95% confidence interval [CI] 1.029-3.644; ≥16 drinks aOR 2.118, 95% CI 1.272-3.527) in contrast to flushers, who showed no significant relationship between hypertriglyceridemia and alcohol consumption. Non-flushers had a significant relationship to low serum high density lipoprotein (HDL) cholesterol levels in four groups (<4 drinks aOR 0.428, 95% CI 0.277-0.662; 4-8 drinks aOR 0.409, 95% CI 0.216-0.774; 8-16 drinks aOR 0.285, 95% CI 0.152-0.536; ≥16 drinks aOR 0.343, 95% CI 0.207-0.568), and flushers had a significant relationship in two groups (8-16 drinks aOR 0.234, 95% CI 0.102-0.536; ≥16 drinks aOR 0.342, 95% CI 0.166-0.705).CONCLUSIONS:
Our results suggest that drinking alcohol increases the risk of hypertriglyceridemia in non-flushers and the risk of low HDL cholesterol flushers.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Triglicerídeos
/
Consumo de Bebidas Alcoólicas
/
Hipertrigliceridemia
/
Modelos Logísticos
/
Razão de Chances
/
Colesterol
/
Estudos Transversais
/
Povo Asiático
/
Ingestão de Líquidos
/
Aldeído Desidrogenase
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Health Promotion
Ano de publicação:
2016
Tipo de documento:
Artigo
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