Combination pharmacotherapy in lipid management
Journal of the Korean Medical Association
;
: 745-749, 2015.
Artigo
em Coreano
| WPRIM
| ID: wpr-109184
ABSTRACT
Latest guidelines on lipid management recommend statins as the first-line therapy. Because limited evidence is available on cardiovascular outcomes with varying statin-nonstatin combinations, recommendation levels for these regimens have been weak. However, a recent trial has demonstrated the additive effect of the statin-ezetimibe combination. The statin-fibrate combination has shown an effect in certain subgroups and on diabetic microangiopathy. Recent trials using the statin-niacin combination have been largely negative, whereas the statin-omega-3 fatty acids combination demonstrated a positive effect only in one study. Identifying the benefits and limitations of each combination is important for the best possible management of patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Inibidores de Hidroximetilglutaril-CoA Redutases
/
Angiopatias Diabéticas
/
Tratamento Farmacológico
/
Ácidos Graxos
/
Ácidos Fíbricos
/
Ezetimiba
/
Niacina
Tipo de estudo:
Guia de Prática Clínica
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Medical Association
Ano de publicação:
2015
Tipo de documento:
Artigo
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