Serial Follow-up of White Matter Connectivity in a Patient with Progressive Multifocal Leukoencephalopathy Presenting Clinical Improvement
Journal of the Korean Neurological Association
;
: 347-351, 2011.
Artigo
em Coreano
| WPRIM
| ID: wpr-109591
ABSTRACT
Progressive multifocal leukoencephalopathy (PML) is a fatal disease that is characterized by progressive demyelination of the cerebral white matter due to JC viral infection. We report serial magnetic resonance spectroscopy (MRS) and tractography changes in a patient with PML. After a three-cycle treatment with cidofovir and cytarabine, the patient exhibited remarkable improvements in motor and cognitive functions. Follow-up MRS and tractography revealed regeneration of the white-matter fibers. This is the first consecutive neuroimaging study showing improvements in neurological symptoms using MRS and tractography.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Regeneração
/
Espectroscopia de Ressonância Magnética
/
Seguimentos
/
Leucoencefalopatia Multifocal Progressiva
/
Doenças Desmielinizantes
/
Citarabina
/
Citosina
/
Neuroimagem
/
Organofosfonatos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Ano de publicação:
2011
Tipo de documento:
Artigo
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