Prevalence of Hepatitis G Virus Infection in Patients with Chronic Renal Failure / 대한간학회지
The Korean Journal of Hepatology
;
: 82-90, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-110187
ABSTRACT
BACKGROUNDS/AIMS:
To investigate the prevalence and clinical implications of hepatitis G virus (HGV) infection in patients with chronic renal failure, a cross-sectional study of 131 hemodialysis patients and 33 kidney transplantation recipients was conducted.METHODS:
HGV RNA was amplified by reverse-transcription (RT) polymerase chain reaction (PCR) assay with primers from the 5'-untranslated region of the viral genome.RESULTS:
The prevalence of HGV infection in patients with chronic renal failure was 25%(41/164). The following factors were taken into consideration the mean age(43.15+/-11.97 years vs 46.46+/-13.08 years), the male to female ratio(2.151 vs 1.861), the mean of the dialysis duration(4.58+/-3.18 years vs 3.90+/-3.31 years), transfusion history (75.6% vs 62.6%), the mean of the ALT level during the prior 6 months(25.78+/-21.50 IU/L vs 23.00+/-59.49 IU/L), and the amount of transfusion(6.22+/-8.03 units vs 5.74+/-9.44 units). The anti-HCV(4.88% vs 8.94%) showed no difference between HGV RNA positive and negative group. The HBsAg positive ratio was 19.5% and 5.81% in HGV RNA positive group and negative group, respectively.CONCLUSION:
The prevalence of HGV infection in patients with chronic renal failure was 25%. There was a higher rate of HBsAg positivity in the HGV RNA positive group rather than in the negative group. HGV infection did not seem to be associated with clinically significant hepatitis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
RNA
/
Reação em Cadeia da Polimerase
/
Prevalência
/
Estudos Transversais
/
Diálise Renal
/
Transplante de Rim
/
Genoma Viral
/
Vírus GB C
/
Diálise
/
Hepatite
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Hepatology
Ano de publicação:
2000
Tipo de documento:
Artigo
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