Corticobasal Degeneration Presenting as Non-Fluent/Agrammatic Primary Progressive Aphasia: A Case Report
Dementia and Neurocognitive Disorders
;
: 55-58, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-11101
ABSTRACT
BACKGROUND:
Non-fluent agrammatic primary progressive aphasia (naPPA) is characterized by progressive non-fluent speech disorder and might be associated with taupathy such as corticobasal degeneration (CBD) and progressive supranuclear palsy. We report a case of overlap syndrome presented with language impairment, and diagnosed as naPPA with possible CBD. CASE REPORT A 58-year-old woman visited a memory and dementia clinic, with a 10-month history of progressive language disturbance. She was diagnosed as naPPA and overlapping CBD, based on the clinical features and neuroimaging findings including florbetaben PET.CONCLUSIONS:
naPPA is pathologically caused by taupathy, and might progress to asymmetrical parkinsonism and apraxia, suggestive of CBD. Overlapping clinical features in our case represent various phenotypes of taupathy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Apraxias
/
Fenótipo
/
Paralisia Supranuclear Progressiva
/
Afasia Primária Progressiva
/
Transtornos Parkinsonianos
/
Demência
/
Neuroimagem
/
Memória
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Dementia and Neurocognitive Disorders
Ano de publicação:
2016
Tipo de documento:
Artigo
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