A Study on the Effects of Taking the Drink Containing Benzoic Acid on Analysis of Hippuric Acid in Urine
Korean Journal of Aerospace and Environmental Medicine
;
: 235-240, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-111086
ABSTRACT
BACKGROUND:
Benzoic acid contained in some food can hinder the biological monitoring of hippuric acid in urine, which is frequently used as an exposure index of toluene and xylene.METHOD:
20 male examinees who are not exposed to organic solvents in their jobs were given a bottle of drink containing benzoic acid(70 mg/dl) and took it. Urine samples were taken from every person just before, in 1.5 hrs after, and in 3 hrs after taking the drink. Hippuric acid in urine was analyzed with improved Ogata and Taguchi method and creatinine with Jaffe method.RESULT:
Mean hippuric acid concentrations in urine just before, in 1.5 hrs after, and in 3 hrs after taking the drink were 0.59+/-0.21 g/g creatinine, 2.75+/-0.98 g/g creatinine, 1.04+/-0.58 g/g creatinine, respectively. And, each group had statistically significant differences (p<0.01). There were no statistically significant differences between two groups categorized by age, smoking, and drinking.CONCLUSION:
From the results, we suggest that when hippuric acid concentration in urine is used as a exposure index of toluene, it should be surveyed whether the food containing benzoic acid was taken or not.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fumaça
/
Solventes
/
Tolueno
/
Xilenos
/
Fumar
/
Monitoramento Ambiental
/
Ácido Benzoico
/
Creatinina
/
Ingestão de Líquidos
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Aerospace and Environmental Medicine
Ano de publicação:
2000
Tipo de documento:
Artigo
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